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How to target apoptosis signaling pathways for the treatment of pediatric cancers

Apoptosis represents one of the most important forms of cell death in higher organisms and is typically dysregulated in human cancers, including pediatric tumors. This implies that ineffective engagement of cell death programs can contribute to tumor formation as well as tumor progression. In additi...

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Detalles Bibliográficos
Autor principal: Fulda, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572677/
https://www.ncbi.nlm.nih.gov/pubmed/23420072
http://dx.doi.org/10.3389/fonc.2013.00022