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Modeling tumor evolutionary dynamics

Tumorigenesis can be seen as an evolutionary process, in which the transformation of a normal cell into a tumor cell involves a number of limiting genetic and epigenetic events, occurring in a series of discrete stages. However, not all mutations in a cell are directly involved in cancer development...

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Detalles Bibliográficos
Autores principales: Stransky, Beatriz, de Souza, Sandro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572685/
https://www.ncbi.nlm.nih.gov/pubmed/23420281
http://dx.doi.org/10.3389/fphys.2012.00480