Combined Inhibition of ErbB1/2 and Notch Receptors Effectively Targets Breast Ductal Carcinoma In Situ (DCIS) Stem/Progenitor Cell Activity Regardless of ErbB2 Status

Pathways involved in DCIS stem and progenitor signalling are poorly understood yet are critical to understand DCIS biology and to develop new therapies. Notch and ErbB1/2 receptor signalling cross talk has been demonstrated in invasive breast cancer, but their role in DCIS stem and progenitor cells...

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Detalles Bibliográficos
Autores principales: Farnie, Gillian, Willan, Pamela M., Clarke, Robert B., Bundred, Nigel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572946/
https://www.ncbi.nlm.nih.gov/pubmed/23457626
http://dx.doi.org/10.1371/journal.pone.0056840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572946/
https://www.ncbi.nlm.nih.gov/pubmed/23457626
http://dx.doi.org/10.1371/journal.pone.0056840

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