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Inhibitory Effects of Resveratrol on PDGF-BB-Induced Retinal Pigment Epithelial Cell Migration via PDGFRβ, PI3K/Akt and MAPK pathways

PURPOSE: In diseases such as proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy, and age-related macular degeneration, retinal pigment epithelial (RPE) cells proliferate and migrate. Moreover, platelet-derived growth factor (PDGF) has been shown to enhance proliferation and mi...

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Detalles Bibliográficos
Autores principales: Chan, Chi-Ming, Chang, Hsun-Hsien, Wang, Vin-Chi, Huang, Chuen-Lin, Hung, Chi-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572951/
https://www.ncbi.nlm.nih.gov/pubmed/23457620
http://dx.doi.org/10.1371/journal.pone.0056819