Expression of stem cell factor in gastrointestinal stromal tumors: Implications for proliferation and imatinib resistance

KIT autophosphorylation caused by mutation of KIT is considered to be a critical mechanism for the oncogenesis of gastrointestinal stromal tumors (GISTs). However, little is known regarding whether stem cell factor (SCF), the KIT ligand, is able to induce the proliferation of GIST cells by activatin...

Descripción completa

Detalles Bibliográficos
Autores principales: HOU, XIAO-WEI, BAI, CHEN-GUANG, LIU, XIAO-HONG, QIU, CEN, HUANG, LING, XU, JING-JING, MA, DA-LIE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572958/
https://www.ncbi.nlm.nih.gov/pubmed/23420128
http://dx.doi.org/10.3892/ol.2012.1019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572958/
https://www.ncbi.nlm.nih.gov/pubmed/23420128
http://dx.doi.org/10.3892/ol.2012.1019

Ejemplares similares