Cargando…

Multi-Population Classical HLA Type Imputation

Statistical imputation of classical HLA alleles in case-control studies has become established as a valuable tool for identifying and fine-mapping signals of disease association in the MHC. Imputation into diverse populations has, however, remained challenging, mainly because of the additional haplo...

Descripción completa

Detalles Bibliográficos
Autores principales: Dilthey, Alexander, Leslie, Stephen, Moutsianas, Loukas, Shen, Judong, Cox, Charles, Nelson, Matthew R., McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572961/
https://www.ncbi.nlm.nih.gov/pubmed/23459081
http://dx.doi.org/10.1371/journal.pcbi.1002877