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Increasing Sequence Search Sensitivity with Transitive Alignments

Sequence alignment is an important bioinformatics tool for identifying homology, but searching against the full set of available sequences is likely to result in many hits to poorly annotated sequences providing very little information. Consequently, we often want alignments against a specific subse...

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Detalles Bibliográficos
Autores principales: Malde, Ketil, Furmanek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573025/
https://www.ncbi.nlm.nih.gov/pubmed/23457449
http://dx.doi.org/10.1371/journal.pone.0054422