A novel cytogenetic abnormality t(7;8)(p11.2:q11.2) and a four-way Philadelphia translocation in an imatinib mesylate-resistant chronic myeloid leukemia patient

Chronic myelogenous leukemia (CML) is characterized by the Philadelphia (Ph) chromosome, created by a reciprocal translocation t(9:22)(q34;q11) which forms the chimeric gene, BCR-ABL. Variant Ph chromosome translocations involving chromosomes other than 9 and 22 have been identified in 5–10% of CML...

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Detalles Bibliográficos
Autores principales: AL-ACHKAR, WALID, ALJAPAWE, ABDULMUNIM, ALMEDANI, SUHER, LIEHR, THOMAS, WAFA, ABDULSAMAD
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573104/
https://www.ncbi.nlm.nih.gov/pubmed/23420612
http://dx.doi.org/10.3892/ol.2012.1037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573104/
https://www.ncbi.nlm.nih.gov/pubmed/23420612
http://dx.doi.org/10.3892/ol.2012.1037

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