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miR-199a-5p Is Upregulated during Fibrogenic Response to Tissue Injury and Mediates TGFbeta-Induced Lung Fibroblast Activation by Targeting Caveolin-1

As miRNAs are associated with normal cellular processes, deregulation of miRNAs is thought to play a causative role in many complex diseases. Nevertheless, the precise contribution of miRNAs in fibrotic lung diseases, especially the idiopathic form (IPF), remains poorly understood. Given the poor re...

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Detalles Bibliográficos
Autores principales: Lino Cardenas, Christian Lacks, Henaoui, Imène Sarah, Courcot, Elisabeth, Roderburg, Christoph, Cauffiez, Christelle, Aubert, Sébastien, Copin, Marie-Christine, Wallaert, Benoit, Glowacki, François, Dewaeles, Edmone, Milosevic, Jadranka, Maurizio, Julien, Tedrow, John, Marcet, Brice, Lo-Guidice, Jean-Marc, Kaminski, Naftali, Barbry, Pascal, Luedde, Tom, Perrais, Michael, Mari, Bernard, Pottier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573122/
https://www.ncbi.nlm.nih.gov/pubmed/23459460
http://dx.doi.org/10.1371/journal.pgen.1003291