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Using Existing Drugs as Leads for Broad Spectrum Anthelmintics Targeting Protein Kinases

As one of the largest protein families, protein kinases (PKs) regulate nearly all processes within the cell and are considered important drug targets. Much research has been conducted on inhibitors for PKs, leading to a wealth of compounds that target PKs that have potential to be lead anthelmintic...

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Detalles Bibliográficos
Autores principales: Taylor, Christina M., Martin, John, Rao, Ramakrishna U., Powell, Kerrie, Abubucker, Sahar, Mitreva, Makedonka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573124/
https://www.ncbi.nlm.nih.gov/pubmed/23459584
http://dx.doi.org/10.1371/journal.ppat.1003149