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Dasatinib inhibits primary melanoma cell proliferation through morphology-dependent disruption of Src-ERK signaling
New strategies for the treatment of advanced melanoma are urgently required. The RAS/RAF/MAPK pathway and c-Src are deregulated in the majority of malignant melanomas, suggesting that they may interact functionally and are involved in the development and progression of the malignancy. Preclinical st...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573147/ https://www.ncbi.nlm.nih.gov/pubmed/23420605 http://dx.doi.org/10.3892/ol.2012.1066 |