Development of measles virus-based shielded oncolytic vectors: suitability of other paramyxovirus glycoproteins

Antibody-mediated neutralization may interfere with the efficacy of measles virus (MV) oncolysis. To circumvent vector neutralization, we sought to exchange the envelope glycoproteins, hemagglutinin (H) and fusion (F), with those from the non-cross reactive Tupaia paramyxovirus (TPMV). To sustain ef...

Descripción completa

Detalles Bibliográficos
Autores principales: Hudacek, Andrew W., Navaratnarajah, Chanakha K., Cattaneo, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573219/
https://www.ncbi.nlm.nih.gov/pubmed/23306608
http://dx.doi.org/10.1038/cgt.2012.92

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573219/
https://www.ncbi.nlm.nih.gov/pubmed/23306608
http://dx.doi.org/10.1038/cgt.2012.92

Ejemplares similares