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Development of measles virus-based shielded oncolytic vectors: suitability of other paramyxovirus glycoproteins
Antibody-mediated neutralization may interfere with the efficacy of measles virus (MV) oncolysis. To circumvent vector neutralization, we sought to exchange the envelope glycoproteins, hemagglutinin (H) and fusion (F), with those from the non-cross reactive Tupaia paramyxovirus (TPMV). To sustain ef...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573219/ https://www.ncbi.nlm.nih.gov/pubmed/23306608 http://dx.doi.org/10.1038/cgt.2012.92 |