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Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B

A recent clinical study demonstrated that a testosterone supplementation improves functional capacity in elderly female patients suffering from heart failure. These findings prompted us to consider possible mechanisms of testosterone-induced cardioprotection in females. To address this question we h...

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Detalles Bibliográficos
Autores principales: Ballantyne, Thomas, Du, Qingyou, Jovanović, Sofija, Neemo, Andrew, Holmes, Robert, Sinha, Sharabh, Jovanović, Aleksandar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573229/
https://www.ncbi.nlm.nih.gov/pubmed/23085378
http://dx.doi.org/10.1016/j.biocel.2012.10.005