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Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome

Perhexiline is a potent anti-anginal drug used for treatment of refractory angina and other forms of heart disease. It provides an oxygen sparing effect in the myocardium by creating a switch from fatty acid to glucose metabolism through partial inhibition of carnitine palmitoyltransferase 1 and 2....

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Detalles Bibliográficos
Autores principales: Yin, Xiaoke, Dwyer, Joseph, Langley, Sarah R., Mayr, Ursula, Xing, Qiuru, Drozdov, Ignat, Nabeebaccus, Adam, Shah, Ajay M., Madhu, Basetti, Griffiths, John, Edwards, Lindsay M., Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573230/
https://www.ncbi.nlm.nih.gov/pubmed/23277191
http://dx.doi.org/10.1016/j.yjmcc.2012.12.014