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Effects of perhexiline-induced fuel switch on the cardiac proteome and metabolome
Perhexiline is a potent anti-anginal drug used for treatment of refractory angina and other forms of heart disease. It provides an oxygen sparing effect in the myocardium by creating a switch from fatty acid to glucose metabolism through partial inhibition of carnitine palmitoyltransferase 1 and 2....
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573230/ https://www.ncbi.nlm.nih.gov/pubmed/23277191 http://dx.doi.org/10.1016/j.yjmcc.2012.12.014 |