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p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts

Pre-clinical studies suggest that the p38 MAPK signaling pathway plays a detrimental role in cardiac remodeling, but its role in cardiac fibroblast (CF) function is not well defined. We aimed to identify the p38 MAPK subtypes expressed by human CF, study their activation in response to proinflammato...

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Detalles Bibliográficos
Autores principales: Sinfield, John K., Das, Anupam, O’Regan, David J., Ball, Stephen G., Porter, Karen E., Turner, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573232/
https://www.ncbi.nlm.nih.gov/pubmed/23206705
http://dx.doi.org/10.1016/j.bbrc.2012.11.071