Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection

When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-, leucine-rich-repeat-containing proteins (NLR proteins) that bind and activate caspase-1. We report that these inflammasome components also regulate autophag...

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Detalles Bibliográficos
Autores principales: Byrne, Brenda G., Dubuisson, Jean-Francois, Joshi, Amrita D., Persson, Jenny J., Swanson, Michele S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573666/
https://www.ncbi.nlm.nih.gov/pubmed/23404401
http://dx.doi.org/10.1128/mBio.00620-12

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573666/
https://www.ncbi.nlm.nih.gov/pubmed/23404401
http://dx.doi.org/10.1128/mBio.00620-12

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