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Inflammasome Components Coordinate Autophagy and Pyroptosis as Macrophage Responses to Infection
When microbes contaminate the macrophage cytoplasm, leukocytes undergo a proinflammatory death that is initiated by nucleotide-binding-domain-, leucine-rich-repeat-containing proteins (NLR proteins) that bind and activate caspase-1. We report that these inflammasome components also regulate autophag...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Microbiology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573666/ https://www.ncbi.nlm.nih.gov/pubmed/23404401 http://dx.doi.org/10.1128/mBio.00620-12 |