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Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia
BACKGROUND: Acute lymphoblastic leukemia (ALL) diagnosed within the first month of life is classified as congenital ALL and has a significantly worse outcome than ALL diagnosed in older children. This suggests that congenital ALL is a biologically different disease, and thus may be caused by a disti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573941/ https://www.ncbi.nlm.nih.gov/pubmed/23379653 http://dx.doi.org/10.1186/1471-2407-13-55 |