Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia

BACKGROUND: Acute lymphoblastic leukemia (ALL) diagnosed within the first month of life is classified as congenital ALL and has a significantly worse outcome than ALL diagnosed in older children. This suggests that congenital ALL is a biologically different disease, and thus may be caused by a disti...

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Detalles Bibliográficos
Autores principales: Chang, Vivian Y, Basso, Giuseppe, Sakamoto, Kathleen M, Nelson, Stanley F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573941/
https://www.ncbi.nlm.nih.gov/pubmed/23379653
http://dx.doi.org/10.1186/1471-2407-13-55

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