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Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study

BACKGROUND: Taxane is one of the first line treatments of lung cancer. In order to identify novel single nucleotide polymorphisms (SNPs) that might contribute to taxane response, we performed a genome-wide association study (GWAS) for two taxanes, paclitaxel and docetaxel, using 276 lymphoblastoid c...

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Detalles Bibliográficos
Autores principales: Niu, Nifang, Schaid, Daniel J, Abo, Ryan P, Kalari, Krishna, Fridley, Brooke L, Feng, Qiping, Jenkins, Gregory, Batzler, Anthony, Brisbin, Abra G, Cunningham, Julie M, Li, Liang, Sun, Zhifu, Yang, Ping, Wang, Liewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573965/
https://www.ncbi.nlm.nih.gov/pubmed/23006423
http://dx.doi.org/10.1186/1471-2407-12-422