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Comparing marginal structural models to standard methods for estimating treatment effects of antihypertensive combination therapy

BACKGROUND: Due to time-dependent confounding by blood pressure and differential loss to follow-up, it is difficult to estimate the effectiveness of aggressive versus conventional antihypertensive combination therapies in non-randomized comparisons. METHODS: We utilized data from 22,576 hypertensive...

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Detalles Bibliográficos
Autores principales: Gerhard, Tobias, Delaney, Joseph AC, Cooper-DeHoff, Rhonda M, Shuster, Jonathan, Brumback, Babette A, Johnson, Julie A, Pepine, Carl J, Winterstein, Almut G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573973/
https://www.ncbi.nlm.nih.gov/pubmed/22866767
http://dx.doi.org/10.1186/1471-2288-12-119