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Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis

Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. By hijacking this evolutionary conserved signaling pathway, cancer cells acquire sustaining proliferation ability, leading to modification of physiologic properties neces...

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Detalles Bibliográficos
Autores principales: Maruyama, Eri Ohfuchi, Yu, H-M. Ivy, Jiang, Ming, Fu, Jiang, Hsu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574013/
https://www.ncbi.nlm.nih.gov/pubmed/23457599
http://dx.doi.org/10.1371/journal.pone.0056644