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Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution

Adeno-associated virus (AAV) is an important vector system for human gene therapy. Although use of AAV serotypes can result in efficient myocardial gene transfer, improvements in the transduction efficiency and specificity are still required. As a method for artificial modification and selection of...

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Detalles Bibliográficos
Autores principales: Yang, Lin, Xiao, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574030/
https://www.ncbi.nlm.nih.gov/pubmed/23394344
http://dx.doi.org/10.1186/1743-422X-10-50