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Characterising the Mechanism of Airway Smooth Muscle β(2) Adrenoceptor Desensitization by Rhinovirus Infected Bronchial Epithelial Cells

Rhinovirus (RV) infections account for approximately two thirds of all virus-induced asthma exacerbations and often result in an impaired response to β(2) agonist therapy. Using an in vitro model of RV infection, we investigated the mechanisms underlying RV-induced β(2) adrenoceptor desensitization...

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Detalles Bibliográficos
Autores principales: Van Ly, David, Faiz, Alen, Jenkins, Christine, Crossett, Ben, Black, Judith L., McParland, Brent, Burgess, Janette K., Oliver, Brian G. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574065/
https://www.ncbi.nlm.nih.gov/pubmed/23457497
http://dx.doi.org/10.1371/journal.pone.0056058