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Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart

Lipopolysaccharide (LPS)-induced myocardial dysfunction is caused, at least in part, by mitochondrial dysfunction. Mitochondrial dysfunction and the oxidative damage associated with it are scavenged through various cellular defense systems such as autophagy to prevent harmful effects. Our recent stu...

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Detalles Bibliográficos
Autores principales: Unuma, Kana, Aki, Toshihiko, Funakoshi, Takeshi, Yoshida, Ken-ichi, Uemura, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574118/
https://www.ncbi.nlm.nih.gov/pubmed/23457579
http://dx.doi.org/10.1371/journal.pone.0056526