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Cobalt Protoporphyrin Accelerates TFEB Activation and Lysosome Reformation during LPS-Induced Septic Insults in the Rat Heart
Lipopolysaccharide (LPS)-induced myocardial dysfunction is caused, at least in part, by mitochondrial dysfunction. Mitochondrial dysfunction and the oxidative damage associated with it are scavenged through various cellular defense systems such as autophagy to prevent harmful effects. Our recent stu...
Autores principales: | Unuma, Kana, Aki, Toshihiko, Funakoshi, Takeshi, Yoshida, Ken-ichi, Uemura, Koichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574118/ https://www.ncbi.nlm.nih.gov/pubmed/23457579 http://dx.doi.org/10.1371/journal.pone.0056526 |
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