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Use of a Molecular Decoy to Segregate Transport from Antigenicity in the FrpB Iron Transporter from Neisseria meningitidis

FrpB is an outer membrane transporter from Neisseria meningitidis, the causative agent of meningococcal meningitis. It is a member of the TonB-dependent transporter (TBDT) family and is responsible for iron uptake into the periplasm. FrpB is subject to a high degree of antigenic variation, principal...

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Detalles Bibliográficos
Autores principales: Saleem, Muhammad, Prince, Stephen M., Rigby, Stephen E. J., Imran, Muhammad, Patel, Hema, Chan, Hannah, Sanders, Holly, Maiden, Martin C. J., Feavers, Ian M., Derrick, Jeremy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574120/
https://www.ncbi.nlm.nih.gov/pubmed/23457610
http://dx.doi.org/10.1371/journal.pone.0056746