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Use of a Molecular Decoy to Segregate Transport from Antigenicity in the FrpB Iron Transporter from Neisseria meningitidis
FrpB is an outer membrane transporter from Neisseria meningitidis, the causative agent of meningococcal meningitis. It is a member of the TonB-dependent transporter (TBDT) family and is responsible for iron uptake into the periplasm. FrpB is subject to a high degree of antigenic variation, principal...
Autores principales: | Saleem, Muhammad, Prince, Stephen M., Rigby, Stephen E. J., Imran, Muhammad, Patel, Hema, Chan, Hannah, Sanders, Holly, Maiden, Martin C. J., Feavers, Ian M., Derrick, Jeremy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574120/ https://www.ncbi.nlm.nih.gov/pubmed/23457610 http://dx.doi.org/10.1371/journal.pone.0056746 |
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