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RhoA/Rho-Kinase and Nitric Oxide in Vascular Reactivity in Rats with Endotoxaemia

RhoA/Rho-kinase (RhoA/ROK) pathway promotes vasoconstriction by calcium sensitivity mechanism. LPS causes nitric oxide (NO) overproduction to induce vascular hyporeactivity. Thus, we tried to examine the role of RhoA/ROK and NO in the regulation of vascular reactivity in different time-point of endo...

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Detalles Bibliográficos
Autores principales: Liao, Mei-Hui, Shih, Chih-Chin, Tsao, Cheng-Ming, Chen, Shiu-Jen, Wu, Chin-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574133/
https://www.ncbi.nlm.nih.gov/pubmed/23457552
http://dx.doi.org/10.1371/journal.pone.0056331