The Epitope of Monoclonal Antibodies Blocking Erythrocyte Invasion by Plasmodium falciparum Map to The Dimerization and Receptor Glycan Binding Sites of EBA-175

The malaria parasite, Plasmodium falciparum, and related parasites use a variety of proteins with Duffy-Binding Like (DBL) domains to bind glycoproteins on the surface of host cells. Among these proteins, the 175 kDa erythrocyte binding antigen, EBA-175, specifically binds to glycophorin A on the su...

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Detalles Bibliográficos
Autores principales: Ambroggio, Xavier, Jiang, Lubin, Aebig, Joan, Obiakor, Harold, Lukszo, Jan, Narum, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574135/
https://www.ncbi.nlm.nih.gov/pubmed/23457550
http://dx.doi.org/10.1371/journal.pone.0056326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574135/
https://www.ncbi.nlm.nih.gov/pubmed/23457550
http://dx.doi.org/10.1371/journal.pone.0056326

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