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The Epitope of Monoclonal Antibodies Blocking Erythrocyte Invasion by Plasmodium falciparum Map to The Dimerization and Receptor Glycan Binding Sites of EBA-175
The malaria parasite, Plasmodium falciparum, and related parasites use a variety of proteins with Duffy-Binding Like (DBL) domains to bind glycoproteins on the surface of host cells. Among these proteins, the 175 kDa erythrocyte binding antigen, EBA-175, specifically binds to glycophorin A on the su...
Autores principales: | Ambroggio, Xavier, Jiang, Lubin, Aebig, Joan, Obiakor, Harold, Lukszo, Jan, Narum, David L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574135/ https://www.ncbi.nlm.nih.gov/pubmed/23457550 http://dx.doi.org/10.1371/journal.pone.0056326 |
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