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Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E

The HOXB13 missense mutation G84E (rs138213197) is associated with increased risk of prostate cancer, but the current estimate of increased risk has a wide confidence interval (width of 95% confidence interval (CI) >200-fold) so the point estimate of 20-fold increased risk could be misleading. Po...

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Detalles Bibliográficos
Autores principales: MacInnis, Robert J., Severi, Gianluca, Baglietto, Laura, Dowty, James G., Jenkins, Mark A., Southey, Melissa C., Hopper, John L., Giles, Graham G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574137/
https://www.ncbi.nlm.nih.gov/pubmed/23457453
http://dx.doi.org/10.1371/journal.pone.0054727