Cargando…

The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway

FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogenesis is not well characterised. Here we investigate...

Descripción completa

Detalles Bibliográficos
Autores principales: Yakkundi, Anita, McCallum, Lynn, O’Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D., McClements, Lana, Elliott, Christopher, McCarthy, Helen O., Hirst, David G., Robson, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574160/
https://www.ncbi.nlm.nih.gov/pubmed/23457460
http://dx.doi.org/10.1371/journal.pone.0055075