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The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway
FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogenesis is not well characterised. Here we investigate...
Autores principales: | Yakkundi, Anita, McCallum, Lynn, O’Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D., McClements, Lana, Elliott, Christopher, McCarthy, Helen O., Hirst, David G., Robson, Tracy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574160/ https://www.ncbi.nlm.nih.gov/pubmed/23457460 http://dx.doi.org/10.1371/journal.pone.0055075 |
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