Na(+) Regulation in the Malaria Parasite Plasmodiumfalciparum Involves the Cation ATPase PfATP4 and Is a Target of the Spiroindolone Antimalarials

The malaria parasite Plasmodium falciparum establishes in the host erythrocyte plasma membrane new permeability pathways that mediate nutrient uptake into the infected cell. These pathways simultaneously allow Na(+) influx, causing [Na(+)] in the infected erythrocyte cytosol to increase to high leve...

Descripción completa

Detalles Bibliográficos
Autores principales: Spillman, Natalie J., Allen, Richard J.W., McNamara, Case W., Yeung, Bryan K.S., Winzeler, Elizabeth A., Diagana, Thierry T., Kirk, Kiaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574224/
https://www.ncbi.nlm.nih.gov/pubmed/23414762
http://dx.doi.org/10.1016/j.chom.2012.12.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574224/
https://www.ncbi.nlm.nih.gov/pubmed/23414762
http://dx.doi.org/10.1016/j.chom.2012.12.006

Ejemplares similares