Casein Kinase 2 Reverses Tail-Independent Inactivation of Kinesin-1

Kinesin-1 is a plus-end microtubule-based motor, and defects in kinesin-based transport are linked to diseases including neurodegeneration. Kinesin can auto-inhibit via a head-tail interaction, but is believed to be active otherwise. Here we report a tail-independent inactivation of kinesin, reversi...

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Detalles Bibliográficos
Autores principales: Xu, Jing, Reddy, Babu J. N., Anand, Preetha, Shu, Zhanyong, Cermelli, Silvia, Mattson, Michelle K., Tripathy, Suvranta K., Hoss, Matthew T., James, Nikita S., King, Stephen J., Huang, Lan, Bardwell, Lee, Gross, Steven P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574636/
https://www.ncbi.nlm.nih.gov/pubmed/22453827
http://dx.doi.org/10.1038/ncomms1760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574636/
https://www.ncbi.nlm.nih.gov/pubmed/22453827
http://dx.doi.org/10.1038/ncomms1760

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