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Casein Kinase 2 Reverses Tail-Independent Inactivation of Kinesin-1
Kinesin-1 is a plus-end microtubule-based motor, and defects in kinesin-based transport are linked to diseases including neurodegeneration. Kinesin can auto-inhibit via a head-tail interaction, but is believed to be active otherwise. Here we report a tail-independent inactivation of kinesin, reversi...
Autores principales: | Xu, Jing, Reddy, Babu J. N., Anand, Preetha, Shu, Zhanyong, Cermelli, Silvia, Mattson, Michelle K., Tripathy, Suvranta K., Hoss, Matthew T., James, Nikita S., King, Stephen J., Huang, Lan, Bardwell, Lee, Gross, Steven P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574636/ https://www.ncbi.nlm.nih.gov/pubmed/22453827 http://dx.doi.org/10.1038/ncomms1760 |
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