Tumor-Specific Expression of Organic Anion-Transporting Polypeptides: Transporters as Novel Targets for Cancer Therapy

Members of the organic anion transporter family (OATP) mediate the transmembrane uptake of clinical important drugs and hormones thereby affecting drug disposition and tissue penetration. Particularly OATP subfamily 1 is known to mediate the cellular uptake of anticancer drugs (e.g., methotrexate, d...

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Detalles Bibliográficos
Autores principales: Buxhofer-Ausch, Veronika, Secky, Lena, Wlcek, Katrin, Svoboda, Martin, Kounnis, Valentinos, Briasoulis, Evangelos, Tzakos, Andreas G., Jaeger, Walter, Thalhammer, Theresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574750/
https://www.ncbi.nlm.nih.gov/pubmed/23431456
http://dx.doi.org/10.1155/2013/863539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574750/
https://www.ncbi.nlm.nih.gov/pubmed/23431456
http://dx.doi.org/10.1155/2013/863539

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