Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease

This report represents a detailed description of experiments designed to replicate and extend the findings of a published study on the effects of treating the R6/2 Huntington’s disease (HD) mouse model with ~300 CAG repeats using the pimelic diphenylamide histone deacetylase (HDAC) inhibitor, HDACi...

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Detalles Bibliográficos
Autores principales: Chen, Jane Y., Wang, Elizabeth A., Galvan, Laurie, Huynh, My, Joshi, Prasad, Cepeda, Carlos, Levine, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Preclinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574864/
https://www.ncbi.nlm.nih.gov/pubmed/23437422
http://dx.doi.org/10.1371/currents.hd.ec3547da1c2a520ba959ee7bf8bdd202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574864/
https://www.ncbi.nlm.nih.gov/pubmed/23437422
http://dx.doi.org/10.1371/currents.hd.ec3547da1c2a520ba959ee7bf8bdd202

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