Characterization of the genetic variation present in CYP3A4 in three South African populations

The CYP3A4 enzyme is the most abundant human cytochrome P450 (CYP) and is regarded as the most important enzyme involved in drug metabolism. Inter-individual and inter-population variability in gene expression and enzyme activity are thought to be influenced, in part, by genetic variation. Although...

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Detalles Bibliográficos
Autores principales: Drögemöller, Britt, Plummer, Marieth, Korkie, Lundi, Agenbag, Gloudi, Dunaiski, Anke, Niehaus, Dana, Koen, Liezl, Gebhardt, Stefan, Schneider, Nicol, Olckers, Antonel, Wright, Galen, Warnich, Louise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574981/
https://www.ncbi.nlm.nih.gov/pubmed/23423246
http://dx.doi.org/10.3389/fgene.2013.00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3574981/
https://www.ncbi.nlm.nih.gov/pubmed/23423246
http://dx.doi.org/10.3389/fgene.2013.00017

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