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Topical effects of N-acetyl-L-hydroxyproline on ceramide synthesis and alleviation of pruritus

PURPOSE: N-acetyl-l-hydroxyproline (AHYP) is an acetylated form of l-hydroxyproline that is used to treat skin ulcers and porphyria cutanea tarda. Its other biological and physiological effects on the skin have not been elucidated. We investigated the effects of AHYP on the skin-barrier function, fo...

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Detalles Bibliográficos
Autores principales: Hashizume, Erika, Nakano, Tetsuo, Kamimura, Ayako, Morishita, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575122/
https://www.ncbi.nlm.nih.gov/pubmed/23430142
http://dx.doi.org/10.2147/CCID.S39370