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Subcutaneous trastuzumab: development of a new formulation for treatment of HER2-positive early breast cancer
Trastuzumab is a monoclonal antibody directed against the human epidermal growth factor receptor 2 (HER2). HER2 is amplified or overexpressed in about 15% of breast cancers and is associated with aggressive disease. Clinical benefits of trastuzumab have been established in the treatment of both earl...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575209/ https://www.ncbi.nlm.nih.gov/pubmed/23430730 http://dx.doi.org/10.2147/OTT.S27733 |