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Effects of human Toll-like receptor 1 polymorphisms on ageing

BACKGROUND: Advanced age results in crucial alterations of the innate and adaptive immune system leading to functional defects resulting in infection and chronic diseases. Toll-like receptors (TLR) recognize pathogenic structures and are important in the immune response to infections and vaccination...

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Detalles Bibliográficos
Autores principales: Uciechowski, Peter, Oellig, Eva Maria, Mariani, Erminia, Malavolta, Marco, Mocchegiani, Eugenio, Rink, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575250/
https://www.ncbi.nlm.nih.gov/pubmed/23391127
http://dx.doi.org/10.1186/1742-4933-10-4