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Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction

BACKGROUND: Studies have demonstrated that carbonic anhydrase I (CA1) stimulates calcium salt precipitation and cell calcification, which is an essential step in new bone formation. Our study had reported that CA1 encoding gene has a strong association with rheumatoid arthritis (RA) and ankylosing s...

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Detalles Bibliográficos
Autores principales: Zheng, Yabing, Wang, Lin, Zhang, Wei, Xu, Hengwei, Chang, Xiaotian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575273/
https://www.ncbi.nlm.nih.gov/pubmed/23256642
http://dx.doi.org/10.1186/1471-2474-13-256