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Transgenic mice over-expressing carbonic anhydrase I showed aggravated joint inflammation and tissue destruction
BACKGROUND: Studies have demonstrated that carbonic anhydrase I (CA1) stimulates calcium salt precipitation and cell calcification, which is an essential step in new bone formation. Our study had reported that CA1 encoding gene has a strong association with rheumatoid arthritis (RA) and ankylosing s...
Autores principales: | Zheng, Yabing, Wang, Lin, Zhang, Wei, Xu, Hengwei, Chang, Xiaotian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575273/ https://www.ncbi.nlm.nih.gov/pubmed/23256642 http://dx.doi.org/10.1186/1471-2474-13-256 |
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