Cargando…

Mojo Hand, a TALEN design tool for genome editing applications

BACKGROUND: Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a cons...

Descripción completa

Detalles Bibliográficos
Autores principales: Neff, Kevin L, Argue, David P, Ma, Alvin C, Lee, Han B, Clark, Karl J, Ekker, Stephen C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575288/
https://www.ncbi.nlm.nih.gov/pubmed/23323762
http://dx.doi.org/10.1186/1471-2105-14-1