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Mojo Hand, a TALEN design tool for genome editing applications
BACKGROUND: Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a cons...
Autores principales: | Neff, Kevin L, Argue, David P, Ma, Alvin C, Lee, Han B, Clark, Karl J, Ekker, Stephen C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575288/ https://www.ncbi.nlm.nih.gov/pubmed/23323762 http://dx.doi.org/10.1186/1471-2105-14-1 |
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