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Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-gamma production and bioinformatics prediction

BACKGROUND: Severe acute respiratory syndrome (SARS) is an emerging infectious disease caused by the novel coronavirus SARS-CoV. The T cell epitopes of the SARS CoV spike protein are well known, but no systematic evaluation of the functional and structural roles of each residue has been reported for...

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Detalles Bibliográficos
Autores principales: Huang, Jun, Cao, Yingnan, Bu, Xianzhang, Wu, Changyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575293/
https://www.ncbi.nlm.nih.gov/pubmed/22963340
http://dx.doi.org/10.1186/1471-2172-13-50