Induction of IFNα or IL-12 depends on differentiation of THP-1 cells in dengue infections without and with antibody enhancement

BACKGROUND: Appropriate induction of the early Th1 cytokine IL-12 is a critical defense directed against viral infection. We have previously shown that different viruses elicited either IL-12 or IFNα dependent Th1 reactions. Using dengue-2 virus, we sought to explore how dengue-2 induced IL-12 or IF...

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Detalles Bibliográficos
Autores principales: Chen, Rong-Fu, Wang, Lin, Cheng, Jiin-Tsuey, Yang, Kuender D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575308/
https://www.ncbi.nlm.nih.gov/pubmed/23216989
http://dx.doi.org/10.1186/1471-2334-12-340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575308/
https://www.ncbi.nlm.nih.gov/pubmed/23216989
http://dx.doi.org/10.1186/1471-2334-12-340

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